Thank you for your interest in our research study entitled: Chronic Pain, Motor Output and Motor Learning in Knee OA

The reason we are doing this study is that some people with knee arthritis have buckling in the knee. Their knee muscles also contract a lot that causes them to walk with less knee motion. Knee buckling and less knee motion can cause arthritis to worsen so clinicians need to find ways to help patients learn to contract their muscles to keep the knee from buckling and to increase knee motion to slow or stop progression of the arthritis.

People who have pain for a long time can have changes in the way they feel pain and other sensations. Pain that lasts for a long time can also change the way that muscles behave during physical activities. In order to invent treatments to improve the way that people with knee arthritis use their muscles, it is important to understand exactly how pain affects a person’s ability to learn new ways to use their muscles.

In this research study we will see how pain from knee arthritis affects movement and muscle activation patterns as well as the ability to learn new movement patterns. The results will help clinicians develop treatment programs that will be most effective in reducing pain, improving function, and slowing arthritis progression in people who have experienced pain for a long time. We will be recruiting individuals both with and without knee pain.

This study will include 2 sessions, each roughly 3-4 hours long. These sessions will include a variety of tests looking at how your knees move, how your knee muscles produce force, and how you feel pain and other sensations. You will need to wear loose fitting shorts (can provide if needed) and comfortable sneakers/walking shoes.

in Session I we will have you:

  • Complete questionnaires about pain, function and how the pain affects you
  • Tell us how you feel sensations on the back of your knee
  • Tell us the smallest amount of pressure that feels painful when pressure is applied around your knees and a finger, and when you put your hand in ice water for no more than 60 seconds.
  • While wearing a blindfold and headphones, we will move your leg very slowly and you will tell us when you feel the movement and the direction of movement
  • Step onto a treadmill when the belt is still or moving and we will measure how your body moves and how the muscles are coordinated

In Session II we will have you:

  • Do some every-day tasks (getting up from a chair and walking, going up and down one flight of stairs) and we will time you with a stop watch
  • Produce force with your knee muscles as quickly as you can
  • Repeat the activities on the treadmill where you step onto a treadmill belt that is still or moving and we will measure how your body moves and how the muscles are coordinated. We repeat this to see whether your body remembers what it did in session I.

In both sessions, we will place small reflective balls on your body that help us measure your movements. Small adhesive sensors will be put on the skin over your muscles to record how your muscles are coordinated.

The information you provide in this form begins the process of seeing if you are eligible to participate in the study. a member of the researh team will review your responses and contact you to discuss your participation in the study.

This questionnaire and your participation is completely voluntary and you are free to discontinue this questionnaire or your participation in the research at any time.

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